Reference library
The calcium sensor synaptotagmin 7 is required for synaptic facilitation.
Paper summary
Identifies synaptotagmin 7 as a calcium sensor required for synaptic facilitation at multiple tested synapses. Repeated presynaptic activity can increase subsequent transmitter release through a mechanism distinct from immediate release sensing.
Relevance to the project
A biological reference for contact-local short-term state and use-dependent communication. Such memory could coexist with slower weight adaptation.
A molecular requirement does not prescribe a particular abstract facilitation equation.
Source record
- Reference ID
- doi-10-1038-nature16507
- Archived version
- PMC article HTML; manuscript/publication label retained in source
- Summary provenance
- reference-library/papers/doi-10-1038-nature16507/metadata.json · summary
- Review status
- initial orientation summary; not a critical full-paper review
- Reading scope
- Selected abstract/opening and available closing discussion/conclusion passages in the preserved text extract; broader project notes provide context. No reproduction of experiments, exhaustive methods review, or equation/figure audit.