Reference library
AMPA receptor trafficking and its role in heterosynaptic plasticity.
Paper summary
Models AMPA-receptor trafficking in a three-dimensional spiny dendritic segment. Strengthening or weakening one synapse changes receptor availability at nearby unstimulated synapses, producing compensatory heterosynaptic effects and altering later plasticity.
Relevance to the project
A mechanism lead for interactions among incoming contacts rather than fully independent weight updates. Could test whether neuron-local shared state provides useful regulation.
The reported effects arise in a particular computational biophysical model.
Source record
- Reference ID
- doi-10-1038-s41598-018-28581-w
- Archived version
- Publisher/repository PDF linked by Europe PMC; see source
- Summary provenance
- reference-library/papers/doi-10-1038-s41598-018-28581-w/metadata.json · summary
- Review status
- initial orientation summary; not a critical full-paper review
- Reading scope
- Selected abstract/opening and available closing discussion/conclusion passages in the preserved text extract; broader project notes provide context. No reproduction of experiments, exhaustive methods review, or equation/figure audit.