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Genotype-phenotype mapping and the end of the 'genes as blueprint' metaphor.

Paper summary

Reviews genotype-to-phenotype mapping and critiques the blueprint metaphor. Developmental processes, environmental context, and nonlinear interactions mediate the transformation from inherited information to realized traits.

Relevance to the project

Directly supports treating an evolved builder as a developmental process. Record how mutations affect realized network structure rather than assuming genotype edits map locally to phenotype.

Genetic representationsDevelopment and morphogenesis

A conceptual critique does not select a particular builder encoding.

Source record

Reference ID
doi-10-1098-rstb-2009-0241
Archived version
Publisher/repository PDF linked by Europe PMC; see source
Summary provenance
reference-library/papers/doi-10-1098-rstb-2009-0241/metadata.json · summary
Review status
initial orientation summary; not a critical full-paper review
Reading scope
Selected abstract/opening and available closing discussion/conclusion passages in the preserved text extract; broader project notes provide context. No reproduction of experiments, exhaustive methods review, or equation/figure audit.