Reference library
Graded synaptic transmission at the Caenorhabditis elegans neuromuscular junction
Paper summary
Optogenetic manipulation at the worm neuromuscular junction shows graded neurotransmitter release. Responses scale with depolarization and include tonic release modulated by hyperpolarization, rather than relying solely on discrete spikes.
Relevance to the project
Supports keeping continuous-valued communication as a legitimate biological analogy. The project's output H need not become spiking solely to resemble neurons.
The study does not imply all nervous systems use graded signaling.
Source record
- Reference ID
- pdf-https-jorgensen-biology-utah-edu-20-20manuscripts-20pdfs-2009-20liu-20graded-20synapse-pdf
- Archived version
- Direct PDF cited in project notes; publication status needs source-specific inspection
- Summary provenance
- reference-library/papers/pdf-https-jorgensen-biology-utah-edu-20-20manuscripts-20pdfs-2009-20liu-20graded-20synapse-pdf/metadata.json · summary
- Review status
- initial orientation summary; not a critical full-paper review
- Reading scope
- Selected abstract/opening and available closing discussion/conclusion passages in the preserved text extract; broader project notes provide context. No reproduction of experiments, exhaustive methods review, or equation/figure audit.