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Metabolic costs and evolutionary implications of human brain development.

Paper summary

Combines brain glucose-use estimates with body-growth data across development. The study finds high childhood brain metabolic demand and examines its relationship to slow body growth and human developmental evolution.

Relevance to the project

Supports separating neural computation and developmental costs in a future modeled energy budget. It offers biological context rather than a conversion factor for the current ledger.

Brain energy useBiological neuronsDevelopment and morphogenesis

Glucose use and total energy expenditure are not interchangeable measurements.

Source record

Reference ID
pmc-pmc4246958
Archived version
Published PNAS PDF publicly hosted in an independent research archive
Summary provenance
reference-library/papers/pmc-pmc4246958/metadata.json · summary
Review status
initial orientation summary; not a critical full-paper review
Reading scope
Selected abstract/opening and available closing discussion/conclusion passages in the preserved text extract; broader project notes provide context. No reproduction of experiments, exhaustive methods review, or equation/figure audit.