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Persistently active neurons in human medial frontal and medial temporal lobe support working memory.

Paper summary

Single-neuron recordings during human working-memory tasks identify persistent activity with different roles across medial temporal and frontal regions. Stimulus-specific and task/load-related patterns predict aspects of memory behavior.

Relevance to the project

Supports distinguishing persistent content from general ongoing activity. Could motivate tests for information retention in F state and histories rather than variation alone.

Biological memoryMemoryBiological neurons

Task-related persistence does not demonstrate spontaneous chaos or indefinite memory.

Source record

Reference ID
pmc-pmc5374017
Archived version
PMC article HTML; manuscript/publication label retained in source
Summary provenance
reference-library/papers/pmc-pmc5374017/metadata.json · summary
Review status
initial orientation summary; not a critical full-paper review
Reading scope
Selected abstract/opening and available closing discussion/conclusion passages in the preserved text extract; broader project notes provide context. No reproduction of experiments, exhaustive methods review, or equation/figure audit.