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Neocortical neurogenesis in humans is restricted to development.

Paper summary

Carbon dating of neuronal DNA and labeling evidence indicate little or no detectable postnatal neuron generation in the sampled human neocortex. The paper contrasts developmental neuron production with adult persistence.

Relevance to the project

A counterbalance to hippocampal neurogenesis sources. Helps keep regional neuron lifespan separate from widespread synaptic and structural plasticity.

Biological neuronsNeural population development

Detection limits and sampled regions qualify the broad title.

Source record

Reference ID
pmid-16901981
Archived version
Publisher/repository PDF linked by Europe PMC; see source
Summary provenance
reference-library/papers/pmid-16901981/metadata.json · summary
Review status
initial orientation summary; not a critical full-paper review
Reading scope
Selected abstract/opening and available closing discussion/conclusion passages in the preserved text extract; broader project notes provide context. No reproduction of experiments, exhaustive methods review, or equation/figure audit.