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AMPA receptor incorporation into synapses during LTP: the role of lateral movement and exocytosis.

Paper summary

Images fluorescent AMPA receptors in rat hippocampal slices during long-term potentiation. Most incorporated receptors arrive by lateral diffusion from the spine surface; subsequent exocytosis primarily replenishes dendritic surface pools for later plasticity.

Relevance to the project

Motivates separating contact-local state from neuron-wide resource or trafficking state. A shared finite pool could couple several local updates if later justified.

Biological neuronsSynaptic plasticitySynaptic communication

This cellular experiment does not prescribe a scalar update equation.

Source record

Reference ID
pmid-19914186
Archived version
PMC article HTML; manuscript/publication label retained in source
Summary provenance
reference-library/papers/pmid-19914186/metadata.json · summary
Review status
initial orientation summary; not a critical full-paper review
Reading scope
Selected abstract/opening and available closing discussion/conclusion passages in the preserved text extract; broader project notes provide context. No reproduction of experiments, exhaustive methods review, or equation/figure audit.