Reference library
Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision.
Paper summary
Studies how local inhibitory circuitry regulates quiescent adult hippocampal stem cells. Tonic GABA signaling and receptor manipulations alter exit from quiescence and self-renewal, linking circuit activity to progenitor decisions.
Relevance to the project
A reference for local feedback connecting network activity and neuron production. The project's builder finishes once; runtime birth remains a separate open mechanism.
Stem-cell niche regulation is not mature-neuron self-reproduction.
Source record
- Reference ID
- pmid-22842902
- Archived version
- Europe PMC hosted article; publication/manuscript status is specified in source XML
- Summary provenance
- reference-library/papers/pmid-22842902/metadata.json · summary
- Review status
- initial orientation summary; not a critical full-paper review
- Reading scope
- Selected abstract/opening and available closing discussion/conclusion passages in the preserved text extract; broader project notes provide context. No reproduction of experiments, exhaustive methods review, or equation/figure audit.