Reference library
Differential contributions of Ca<sup>2+</sup> -activated K<sup>+</sup> channels and Na<sup>+</sup> /K<sup>+</sup> -ATPases to the generation of the slow afterhyperpolarization in CA1 pyramidal cells.
Paper summary
Investigates the slow afterhyperpolarization in rat hippocampal neurons near physiological temperature. Calcium-activated potassium currents and sodium-potassium pumps contribute, with pumps dominating some short-spike-train responses.
Relevance to the project
A mechanism lead for history-dependent intrinsic negative feedback and multiple timescales within F. Such regulation could help bound activity without guaranteeing useful dynamics.
Specific ion-channel roles vary with preparation and stimulation.
Source record
- Reference ID
- pmid-29431274
- Archived version
- Europe PMC hosted article; publication/manuscript status is specified in source XML
- Summary provenance
- reference-library/papers/pmid-29431274/metadata.json · summary
- Review status
- initial orientation summary; not a critical full-paper review
- Reading scope
- Selected abstract/opening and available closing discussion/conclusion passages in the preserved text extract; broader project notes provide context. No reproduction of experiments, exhaustive methods review, or equation/figure audit.