Reference library
Modulation of Apoptosis Controls Inhibitory Interneuron Number in the Cortex.
Paper summary
Studies developmental interneuron survival and shows that activity can modulate apoptosis. Changes in interneuron populations and transient depolarization reveal feedback regulating cortical inhibitory-cell number and repertoire.
Relevance to the project
A mechanism lead for activity-dependent neuron survival, distinct from maintenance energy or contact removal. Any runtime lifecycle rule remains unselected.
Developmental population regulation is not a general rule for adult neuronal turnover.
Source record
- Reference ID
- pmid-29444425
- Archived version
- Publisher/repository PDF linked by Europe PMC; see source
- Summary provenance
- reference-library/papers/pmid-29444425/metadata.json · summary
- Review status
- initial orientation summary; not a critical full-paper review
- Reading scope
- Selected abstract/opening and available closing discussion/conclusion passages in the preserved text extract; broader project notes provide context. No reproduction of experiments, exhaustive methods review, or equation/figure audit.